Summary of studies adopted by SMHRN
Addictions Bipolar Depression Eating Disorders Genetic Personality Disoder Learning Disabilities
Psychological Distress Psychosis Schizophrenia Unexplained Symptoms Aspergers Syndrome Autism Other


fNEMO
Neuropsychological function as a result of chronic exposure to methadone and other opiates (NEMO): neural responses to rewards - a study using functional magnetic resonance imaging (fMRI)
Chief Investigator
Dr Alex Baldacchino



A clinical, neuropsychological and magnetic resonance imaging study comparing autism spectrum disorders and schizophrenia spectrum disorders
A clinical, neuropsychological and magnetic resonance imaging study comparing autism spectrum disorders and schizophrenia spectrum disorders
Chief Investigator
Dr Andrew Stanfield



Efficacy of a group based social skills intervention in adults with Asperger syndrome
Efficacy of a group based social skills intervention in adults with Asperger syndrome
Chief Investigator
Dr Andrew Stanfield



CEQUEL
Comparative Evaluation of QUEtiapine-Lamotrigine combination versus quetiapine monotherapy (and folic acid versus placebo) in patients with bipolar depression.
Chief Investigator
Professor John Geddes
BFS
Bipolar Family Study
Chief Investigator
Dr Andrew McIntosh
Molecular Study
Molecular Genetic Investigation of Bipolar Disorder and Related Mood Disorder
Chief Investigator
Professor Nick Craddock
Emotional processing in Bipolar Disorder
Emotional processing in Bipolar Disorder
Chief Investigator
Dr Jess Sussmann
A pilot randomised controlled trial of Cognitive Behaviour Therapy for early bipolar disorder.
A pilot randomised controlled trial of Cognitive Behaviour Therapy for early bipolar disorder.
Chief Investigator
Dr Jamie Kirk



ProCEED
Evaluation of a system of structured, pro-active care for chronic depression in primary care
Chief Investigator
Dr Marta Buszewicz
SMaRT Oncology-2 Trial
Symptom Management Research Trials - SMaRT Oncology-2 Trial
Chief Investigator
Professor Michael Sharpe
SMaRT Oncology-3 Pilot
Symptom Management Research Trials - SMaRT Oncology-3 Pilot
Chief Investigator
Professor Michael Sharpe
SMaRT Oncology-3 Trial
Symptom Management Research Trials - SMaRT Oncology-3 Trial
Chief Investigator
Professor Michael Sharpe
GCIT
Evaluation of cognitive interpersonal group Evaluation of cognitive interpersonal group therapy for psychosis
Chief Investigator
Dr Christine Braehler
Diffusion Tensor and Functional Imaging of Chronic Treatment Refractory Depression and Neurosurgical Treatments
DTFI
Chief Investigator
Prof Douglas Steele
COBALT
Cognitive behavioural therapy as an adjunct to pharmacotherapy for treatment resistant depression in primary care: a randomised controlled trial
Chief Investigator
Dr Nicola Wiles
DBS
A clinical evaluation for the management of patients with Major Depressive Disorder, single or recurrent episode, with deep brain stimulation.
Chief Investigator
Professor Keith Matthews
SPECT
The effects of TNF blockade (using etanercept) on substrates of mood and cognition in patients with inflammatory arthritis.
Chief Investigator
Dr Jonathan Cavanagh
ISA
Inflammatory Bowel Disease, Steroids and Affective Disorder
Chief Investigator
Dr Benjamin Baig
CBASP
Intensive psychotherapy for chronic, treatment-resistant depression: a pilot investigation of clinical effectiveness and mediators of learning in the Cognitive Behavioural Analysis System of Psychotherapy (CBASP)
Chief Investigator
John Swan
KANECT
The use of Ketamine as an anaesthetic during electroconvulsive therapy (ECT) for depression: does it improve treatment outcome?
Chief Investigator
Professor Ian Reid
ASPEN
Anti-Stigma Partnership European Network
Chief Investigator
Professor Graham Thornicroft



iMANTRA-R
Internet-based relapse prevention for in-patients with Anorexia Nervosa
Chief Investigator
Professor Ulrike Schmidt



Scottish Family Genetic Colloboration
Scottish Family Genetic Collaboration
Chief Investigator
Dr Andrew McIntosh
GS SFHS
Generation Scotland: Scottish Family Health Study
Chief Investigator
Professor Andrew Morris



DownsLit
Genetically determined brain abnormalities in Down’s syndrome – towards a treatment
Chief Investigator
Professor Declan Murphy
A multi-centre phase 3 Cluster randomized controlled trial of a manualized anger management intervention for people with mild to moderate learning disabilities
A multi-centre phase 3 Cluster randomized controlled trial of a manualized anger management intervention for people with mild to moderate learning disabilities
Chief Investigator
Professor Paul Willner
NOVARTIS
A randomised, double blind, placebo-controlled, parallel group study to evaluate AFQ056 in adult patients with Fragile X Syndrome
Chief Investigator
Dr Andrew Stanfield



A Neuropsychological Study of Emotion Regulation and Impulsivity
A Neuropsychological Study of Emotion Regulation and Impulsivity
Chief Investigator
Dr Jeremy Hall
ENGAGE
Meeting mental health needs of complex co-morbid patients following a suicide attempt. A pilot study.
Chief Investigator
Prof Kate Davidson



PODS
Persistence of distress in cancer outpatients: a symptom follow-up study
Chief Investigator
Prof Michael Sharpe



EDIE 2
Early Detection and Intervention Evaluation for individuals at high risk of psychosis (2)
Chief Investigator
Dr Anthony Morrison
PACT
Acceptance and Commitment Therapy for Psychosis
Chief Investigator
Dr Ross White



Scottish Family Mental Health Study
Brain imaging studies of pre-frontal glutamate concentration, perfusion and activity.
Chief Investigator
Prof Stephen Lawrie
LD Rescan
Further studies of mental health in young people with additional learning needs.
Chief Investigator
Prof David Owens
Trust in Schizophrenia investigated with an Economics Game Paradigm
Trust in Schizophrenia investigated with an Economics Game Paradigm
Chief Investigator
Dr James Currie
A single sequence, open-label, methodology study to assess cognitive change in patients with schizophrenia after supervised training with the Brain Fitness Program
A single sequence, open-label, methodology study to assess cognitive change in patients with schizophrenia after supervised training with the Brain Fitness Program
Chief Investigator
The Benefit of Minocycline on Negative Symptoms in Schizophrenia: Extent and Mechanisms
The Benefit of Minocycline on Negative Symptoms in Schizophrenia: Extent and Mechanisms
Chief Investigator
Professor Bill Deakin
Roche negative
Study to evaluate efficacy and safety of RO4917838 in stable patients with persistent, predominant negative symptoms of schizophrenia treated with antipsychotics followed by a 28 week, doubleblind treatment period
Chief Investigator
Professor John Geddes
Roche sub-optimal
Study to evaluate the efficacy and safety of RO4917838 in patients with sub-optimally controlled symptoms of schizophrenia treated with antipsychotics followed by a 40-week double-blind, parallel group, placebo-controlled treatment period.
Chief Investigator
Professor John Geddes



MSS
Multiple Symptom Study
Chief Investigator
Dr Chris Burton